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[老年人的医源性或环境所致血管疾病]

[Iatrogenic or environmentally caused vascular diseases in the aged].

作者信息

Schütz R M

出版信息

Aktuelle Gerontol. 1983 Sep;13(5):177-80.

PMID:6139033
Abstract

Cardiovascular diseases show a significant increase with age. However, there are no lesions which especially or exclusively affect blood vessels of old people only. Nevertheless, old persons seem to be more exposed to events occurring in their environment or, for example, during vascular or bone surgery, which can result in such lesions. Hyperergic vascular diseases can also occur and are mostly induced by polypragmasy as a consequence of multimorbidity. Drug-elicited reactions depend on changes in pharmacokinetics or pharmacodynamics. In addition, defects in cardiovascular adaptability may enhance the effectivity of the risks.

摘要

心血管疾病的发病率随年龄显著增加。然而,并没有特别或专门仅影响老年人血管的病变。尽管如此,老年人似乎更容易受到其周围环境中发生的事件影响,或者例如在血管或骨手术期间发生的事件影响,这些事件可能导致此类病变。过敏性血管疾病也可能发生,并且大多是由多重疾病导致的多药合用引起的。药物引起的反应取决于药代动力学或药效学的变化。此外,心血管适应性缺陷可能会增加风险的影响程度。

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