Samonina G E, Hakumäki M O
Scand J Clin Lab Invest. 1983 Sep;43(5):389-92.
Injection of atropine sulphate induces tachycardia in conscious unrestrained cats. Injection of the same dose of atropine sulphate after a beta-blocking agent is accompanied by less severe tachycardia. We suggest that atropine sulphate-induced tachycardia in conscious cats, and in anaesthetized animals, is linked to changes in sympathetic-vagal balance, to activation of sympathetic centres and obviously to muscarinic antagonistic effects of atropine in sympathetic nerves.
注射硫酸阿托品可使清醒自由活动的猫出现心动过速。在给予β受体阻滞剂后注射相同剂量的硫酸阿托品，心动过速的程度较轻。我们认为，硫酸阿托品在清醒猫和麻醉动物中诱发的心动过速与交感-迷走神经平衡的改变、交感神经中枢的激活以及阿托品在交感神经中的毒蕈碱拮抗作用明显相关。
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