同一家族中的双卵双生、隐睾症和精原细胞瘤。

Dizygotic twinning, cryptorchism, and seminoma in a sibship.

作者信息

Anderson K C, Li F P, Marchetto D J

出版信息

Cancer. 1984 Jan 15;53(2):374-6. doi: 10.1002/1097-0142(19840115)53:2<374::aid-cncr2820530234>3.0.co;2-b.

DOI:10.1002/1097-0142(19840115)53:2<374::aid-cncr2820530234>3.0.co;2-b

Abstract

Cryptorchism was diagnosed in all 3 male members of 2 pairs of dizygotic twins in a sibship. Two of these brothers developed seminomas at age 31 and 33 years. Studies revealed a nephew with an atrophic testicle, but no additional instances of twinning, cryptorchism or testis cancer. Cryptorchism has been reported previously in 3 of 8 sets of twins with testis cancer, but rarely in familial testis cancer affecting other relatives. Hormonal factors may be involved in the association of twinning, cryptorchism and testis cancer in this family.

摘要

在一个家族中，两对异卵双胞胎的所有3名男性成员均被诊断为隐睾症。其中两名兄弟分别在31岁和33岁时患上了精原细胞瘤。研究发现一名侄子睾丸萎缩，但没有其他孪生、隐睾症或睾丸癌病例。此前曾有报道称，8组患睾丸癌的双胞胎中有3组存在隐睾症，但在影响其他亲属的家族性睾丸癌中很少见。激素因素可能与该家族中孪生、隐睾症和睾丸癌的关联有关。