Tamura A, Takahashi K
Acta Virol. 1983 Nov;27(6):457-62.
The in vitro production of intracytoplasmic oncovirus A-particles and of atypical mammary tumor virus (MLAV) from a line of DBA/2 mouse leukemia (MLA) cells were compared in the presence of insulin, dexamethasone and 12-0-tetradecanoyl-phorbol-13-acetate (TPA), which are known to stimulate the synthesis of mouse mammary tumor virus. High amounts of A-particles were recovered from cells cultivated in the presence of dexamethasone (1 microgram/ml) as compared to untreated controls; in contrast, the production of MLAV was suppressed. Insulin and TPA did not show any significant effects.
在已知可刺激小鼠乳腺肿瘤病毒合成的胰岛素、地塞米松和12-0-十四烷酰佛波醇-13-乙酸酯（TPA）存在的情况下，比较了从DBA/2小鼠白血病（MLA）细胞系体外产生胞质内肿瘤病毒A颗粒和非典型乳腺肿瘤病毒（MLAV）的情况。与未处理的对照相比，在存在地塞米松（1微克/毫升）的情况下培养的细胞中回收了大量的A颗粒；相反，MLAV的产生受到抑制。胰岛素和TPA没有显示出任何显著影响。
