Maltz E, Olsson K, Glick S M, Fyhrquist F, Silanikove N, Choshniak I, Shkolnik A
Comp Biochem Physiol A Comp Physiol. 1984;77(1):79-84. doi: 10.1016/0300-9629(84)90015-x.
Three lactating and three non-lactating black Bedouin goats were subjected to four days of water deprivation or to hemorrhage. Four days of water deprivation caused body wt losses of 32 and 23% and plasma volume losses of 30 and 34% in lactating and non-lactating goats respectively. Plasma osmolality increased 17 and 15% in lactating and non-lactating goats. Plasma arginine vasopressin concentration rose from about 5 pg/ml to a mean of 36 pg/ml. Plasma renin activity increased from about 0.7 ng/ml/hr to a mean of 3.45 ng/ml/hr in lactating and to 3.15 ng/ml/hr in non-lactating goats. At 4.5 hr post-rehydration plasma osmolality and plasma vasopressin concentration were back to normal in non-lactating, but still elevated in lactating goats. Plasma renin activity increased after rehydration. Rapid blood volume loss of 21-28% increased plasma vasopressin concentration to 16-35 pg/ml in non-lactating and to 70 or greater than 500 pg/ml in lactating goats. It is concluded that black Bedouin goats are well adapted to endure severe dehydration and rapid rehydration, but that they (especially lactating animals) react strongly to rapid volume depletion.
三只处于哺乳期的和三只非哺乳期的黑色贝都因山羊分别经历了四天的禁水或失血过程。四天的禁水导致哺乳期山羊体重分别下降32%和23%，血浆量分别下降30%和34%；非哺乳期山羊体重分别下降23%和32%，血浆量分别下降34%和30%。哺乳期和非哺乳期山羊的血浆渗透压分别升高17%和15%。血浆精氨酸加压素浓度从约5皮克/毫升升至平均36皮克/毫升。哺乳期山羊血浆肾素活性从约0.7纳克/毫升/小时升至平均3.45纳克/毫升/小时，非哺乳期山羊升至3.15纳克/毫升/小时。补液后4.5小时，非哺乳期山羊的血浆渗透压和血浆加压素浓度恢复正常，但哺乳期山羊仍升高。补液后血浆肾素活性增加。21% - 28%的快速失血使非哺乳期山羊血浆加压素浓度升至16 - 35皮克/毫升，哺乳期山羊升至70皮克/毫升或高于500皮克/毫升。得出的结论是，黑色贝都因山羊能够很好地适应严重脱水和快速补液，但它们（尤其是哺乳期动物）对快速的血容量减少反应强烈。
