Stüttgen G
Derm Beruf Umwelt. 1983;31(6):191-5.
Histamine can be presented as neurotransmitter and immunomodulator beside its direct action as mediator of allergic and pseudoallergic responses. Histamine is involved in inhibition or stimulation of metabolic processes which have important in immunological as well in neural processes. The differentiation between H1- und H2-receptors of histamine extends the therapeutical use of antihistaminics in dependence of their pharmacological affinity.
组胺除了作为过敏和类过敏反应的介质具有直接作用外，还可作为神经递质和免疫调节剂。组胺参与抑制或刺激代谢过程，这在免疫过程和神经过程中都很重要。组胺H1和H2受体的区分扩大了抗组胺药根据其药理亲和力的治疗用途。
