Single endometrial aspiration for determination of ovulation.

The possibility of utilizing a single endometrial aspiration for the determination of ovulation was explored and compared with endometrial histology, serial vaginal cytology and plasma progesterone. A total of 180 women with normal, regular cycles and no pelvic pathologic conditions were studied. A correlation of 90.5% was observed between aspiration smears and histology. Vaginal cytology and histology agreed in 71.7% of the cases, while plasma progresterone and endometrial histology correlated in 95% of the women. Endometrial aspiration appeared to be an accurate, quick, inexpensive, convenient and a one-time method, which could be repeated in successive cycles without any patient discomfort.