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十二指肠腺类癌——一种富含生长抑素且与神经内分泌相关的肿瘤。

Glandular duodenal carcinoid--a somatostatin rich tumour with neuroendocrine associations.

作者信息

Griffiths D F, Jasani B, Newman G R, Williams E D, Williams G T

出版信息

J Clin Pathol. 1984 Feb;37(2):163-9. doi: 10.1136/jcp.37.2.163.

DOI:10.1136/jcp.37.2.163
PMID:6141184
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC498672/
Abstract

The clinical and pathological features of four cases of duodenal carcinoid tumour are presented. All four tumours showed a glandular pattern, and in three cases this was associated with psammoma bodies. In three tumours somatostatin was identified by immunocytochemistry in most tumour cells. In two cases the duodenal tumours were associated with von Recklinghausen's disease and phaeochromocytoma. The importance of these unusual features is discussed, and it is suggested that these glandular carcinoids are a specific subgroup of endocrine cell tumours which appear to have potentially important clinical and pathological associations.

摘要

本文报告了4例十二指肠类癌肿瘤的临床和病理特征。所有4个肿瘤均呈腺管样结构,3例伴有砂粒体。3个肿瘤经免疫细胞化学检测发现多数肿瘤细胞中有生长抑素。2例十二指肠肿瘤与冯雷克林霍增氏病及嗜铬细胞瘤有关。文中讨论了这些不寻常特征的重要性,并提示这些腺管样类癌是内分泌细胞瘤的一个特殊亚组,似乎具有潜在重要的临床和病理联系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bda4/498672/cfd5a00eee97/jclinpath00173-0059-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bda4/498672/f21a07c1f260/jclinpath00173-0056-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bda4/498672/481142a90253/jclinpath00173-0057-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bda4/498672/fac9c643b7b2/jclinpath00173-0058-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bda4/498672/cfd5a00eee97/jclinpath00173-0059-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bda4/498672/f21a07c1f260/jclinpath00173-0056-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bda4/498672/481142a90253/jclinpath00173-0057-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bda4/498672/fac9c643b7b2/jclinpath00173-0058-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bda4/498672/cfd5a00eee97/jclinpath00173-0059-a.jpg

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Immunohistochemical distribution of chromogranins A and B and secretogranin II in neuroendocrine tumours of the gastrointestinal tract.

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