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暴露于不同浓度甲苯对雄性大鼠下丘脑去甲肾上腺素神经末梢系统中胺周转增加及催乳素分泌变化的影响。

Increased amine turnover in several hypothalamic noradrenaline nerve terminal systems and changes in prolactin secretion in the male rat by exposure to various concentrations of toluene.

作者信息

Andersson K, Nilsen O G, Toftgard R, Eneroth P, Gustafsson J A, Battistini N, Agnati L F

出版信息

Neurotoxicology. 1983 Winter;4(4):43-55.

PMID:6142437
Abstract

Subacute exposure of rats to varying concentrations of toluene vapours leads to increases of amine levels and turnover in several types of hypothalamic noradrenaline nerve terminal systems. Furthermore, the exposure of toluene in concentrations ranging from 80-3000 ppm and benzene (1500 ppm) produced differential effects on dopamine and noradrenaline turnover within various parts of the hypothalamus. These regions are involved in neuroendocrine regulation and disturbances in the secretion of prolactin were demonstrated after exposure to toluene.

摘要

将大鼠亚急性暴露于不同浓度的甲苯蒸气中，会导致几种类型的下丘脑去甲肾上腺素神经末梢系统中的胺水平和周转率增加。此外，暴露于浓度范围为80 - 3000 ppm的甲苯和1500 ppm的苯中，会对下丘脑各部分内的多巴胺和去甲肾上腺素周转率产生不同影响。这些区域参与神经内分泌调节，并且在暴露于甲苯后证实了催乳素分泌存在紊乱。

相似文献

1
Increased amine turnover in several hypothalamic noradrenaline nerve terminal systems and changes in prolactin secretion in the male rat by exposure to various concentrations of toluene.暴露于不同浓度甲苯对雄性大鼠下丘脑去甲肾上腺素神经末梢系统中胺周转增加及催乳素分泌变化的影响。
Neurotoxicology. 1983 Winter;4(4):43-55.
2
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3
Nicotine-induced increases of noradrenaline turnover in discrete noradrenaline nerve terminal systems of the hypothalamus and the median eminence of the rat and their relationship to changes in the secretion of adenohypophyseal hormones.尼古丁引起大鼠下丘脑和正中隆起离散去甲肾上腺素神经末梢系统中去甲肾上腺素周转率增加及其与腺垂体激素分泌变化的关系。
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