Vassilev V I
Gen Pharmacol. 1984;15(2):167-70. doi: 10.1016/0306-3623(84)90103-4.
Spontaneous contractions of uterine muscle strips from juvenile, anoestral and pregnant sheep were recorded in vitro isometrically. There is a spontaneous contractile activity irrespective of hormonal status of the animals. Acetylcholine increases the tone and frequency of the phasic contractions of uterine corpus and horn preparations from the three groups of animals. The adrenaline excitatory effect on the myometrial contractions was mediated by alpha-adrenoreceptors. The pregnant uterine strips showed strengthening of the inhibitory effect mediated by the beta-adrenoreceptors.
在体外等长记录幼年、非发情期和怀孕绵羊子宫肌条的自发收缩。无论动物的激素状态如何，都存在自发收缩活动。乙酰胆碱可增加三组动物子宫体和子宫角制剂的紧张度和相性收缩频率。肾上腺素对子宫肌层收缩的兴奋作用是由α-肾上腺素能受体介导的。怀孕的子宫肌条显示出由β-肾上腺素能受体介导的抑制作用增强。
