Escande M, Granier F, Girard M
Encephale. 1983;9(4 Suppl 2):273B-277B.
The double-blind controlled trials between benzodiazepines and antidepressants show that benzodiazepines have not specific antidepressive action in depression. The benzodiazepines exert limited effect on the anxiety of endogenous and melancholia. They have definitive properties in neurotic depressions and mixed anxious-depressive states. In theses states, they may extenuate inhibition and elevate mood. Benzodiazepines are primarily anxiolytic rather than antidepressant -- But in some cases, anxiety and depression are not easily distinguished.
苯二氮䓬类药物与抗抑郁药物之间的双盲对照试验表明，苯二氮䓬类药物对抑郁症没有特异性抗抑郁作用。苯二氮䓬类药物对内源性抑郁症和忧郁症的焦虑作用有限。它们在神经症性抑郁症和混合性焦虑抑郁状态中有确切疗效。在这些状态下，它们可以减轻抑制并改善情绪。苯二氮䓬类药物主要是抗焦虑药而非抗抑郁药——但在某些情况下，焦虑和抑郁不易区分。
