Bono A V, Roggia A
J Int Med Res. 1984;12(2):128-31. doi: 10.1177/030006058401200212.
Fifty male children, aged between 3 and 10 years, were treated for a 12-day period with either trimethoprim (80-160 mg) plus sulphamethoxazole (400-800 mg) daily (co-trimoxazole) or 50-125 mg/day flurbiprofen rectally. The patients had been treated surgically for criptorchidism. Flurbiprofen showed good effectivity in controlling post-operative inflammation in urology. It is concluded that antimicrobial agents such as cotrimoxazole, because of their potential risks of damage at the cell's level, should be used only in presence of a bacterial infection.
五十名年龄在3至10岁之间的男童接受了为期12天的治疗，他们要么每天服用甲氧苄啶（80 - 160毫克）加磺胺甲恶唑（400 - 800毫克）（复方新诺明），要么每天直肠给予氟比洛芬50 - 125毫克。这些患者此前因隐睾症接受过手术治疗。氟比洛芬在控制泌尿外科术后炎症方面显示出良好的有效性。得出的结论是，像复方新诺明这样的抗菌药物，由于其在细胞水平上存在潜在的损害风险，应仅在有细菌感染的情况下使用。
