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母亲服用普萘洛尔后胎儿心率对可控声音刺激的反应。

Fetal heart rate response to a controlled sound stimulus after propranolol administration to the mother.

作者信息

Jensen O H

出版信息

Acta Obstet Gynecol Scand. 1984;63(3):199-202. doi: 10.3109/00016348409155496.

DOI:10.3109/00016348409155496
PMID:6145290
Abstract

The fetal heart rate response to a controlled sound stimulus was recorded in 36 pregnant women before and after a maternal peroral dose of either 80 mg propranolol, or placebo. The sound stimulation was repeated 60 minutes, 120 minutes and 180 minutes after the drug administration. The fetal heart rate response to sound was significantly depressed by this moderate dose of propranolol. The sound stimulation method is found to reflect sensitively the immediate influence of propranolol on the fetus.

摘要

对36名孕妇在口服80毫克普萘洛尔或安慰剂前后记录胎儿心率对可控声音刺激的反应。给药后60分钟、120分钟和180分钟重复进行声音刺激。该中等剂量的普萘洛尔显著降低了胎儿心率对声音的反应。发现声音刺激方法能敏感地反映普萘洛尔对胎儿的即时影响。

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