Effect of immunosuppression on morphological changes in CNS of monkeys infected with different measles virus vaccine strains.
作者信息
Sharova O K, Rozina E E, Gordienko N M, Shteinberg L S
出版信息
Acta Virol. 1984 Mar;28(2):144-7.
PMID:6145348
Abstract
Residual neurovirulence of measles virus vaccine strains "Leningrad-16", "Moscow-5" and of cloned variant of L-16 strain--clone 3, differing in the degree of attenuation, was studied in intracerebrally (i.c.) infected Cercopithecus aethiops monkeys, receiving cortisone and/or antilymphocyte serum (ALS). Whereas the sensitivity for detection of the potential neurovirulence of vaccine strains was not increased by cortisone treatment. ALS had such effect in detection of neurotropic properties of the L-16 strain and its cloned variants.
摘要
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