[麻疹病毒L-16疫苗株克隆变异体感染的猴子中枢神经系统中麻疹抗原的持续性]
[Persistence of the measles antigen in the central nervous system of monkeys infected with clonal variants of the L-16 vaccinal strain of the measles virus].
作者信息
Sharova O K, Rozina E E, Gordienko N M, Iakovleva G S, Shteĭnberg L Sh
出版信息
Vopr Virusol. 1983 Jan-Feb;28(1):78-81.
PMID:6845720
Abstract
The time of persistence of measles antigen was studied in Macaca mulatta and green monkeys inoculated intracerebrally with the vaccine L-16 strain of measles virus and its two genetically homologous variants. Two clones differing in their neurovirulence were used. The results of the study showed correlation between the time of the antigen persistence in the central nervous system and the severity of morphological changes.
摘要
在恒河猴和绿猴中研究了麻疹抗原的持续时间，这些猴子经脑内接种麻疹病毒疫苗L-16株及其两个基因同源变体。使用了两种神经毒力不同的克隆。研究结果表明，中枢神经系统中抗原持续时间与形态学变化的严重程度之间存在相关性。
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