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大鼠前胃低酸度及胃食团的作用

Low forestomach acidity in the rat and the role of the gastric bolus.

作者信息

Browning J, O'Brien P, Gannon B J

出版信息

Comp Biochem Physiol A Comp Physiol. 1984;78(1):63-5. doi: 10.1016/0300-9629(84)90093-8.

DOI:10.1016/0300-9629(84)90093-8
PMID:6146438
Abstract

pH measurements were recorded from the mucosal surfaces of the rat forestomach and glandular stomach following stimulation of acid-secretion by pentagastrin. Animals containing a normal gastric bolus showed lower forestomach acidity (pH 4.3, cf. 3.2) as did coprophagic animals that contained a fecal gastric bolus (pH 6.0, cf. 3.6). Animals without a gastric bolus showed higher forestomach acidity (pH 2.3, cf. 3.0). It is concluded that the presence of a food bolus is prerequisite to maintenance of lower forestomach acidity in rats.

摘要

在用五肽胃泌素刺激胃酸分泌后,记录大鼠前胃和腺胃黏膜表面的pH值。含有正常胃食团的动物前胃酸度较低(pH 4.3,对比3.2),而含有粪便性胃食团的食粪动物也是如此(pH 6.0,对比3.6)。没有胃食团的动物前胃酸度较高(pH 2.3,对比3.0)。得出的结论是,食团的存在是维持大鼠前胃较低酸度的先决条件。

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