Yu S J, Ing R T
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1984;78(1):145-52. doi: 10.1016/0742-8413(84)90062-8.
Biphenyl was hydroxylated to 4-hydroxybiphenyl by a mixed-function oxidase system from midgut microsomes of fall armyworm (Spodoptera frugiperda) larvae. Optimum conditions for assaying the enzyme were established. The microsomal biphenyl 4-hydroxylase activity increased during larval development and declined in the prepupa. Allelochemicals (monoterpenes, indoles and flavones), drugs (phenobarbital and 3-methylcholanthrene) and host plants were found to induce the hydroxylase. The enzyme was also found to be fairly active in other species such as velvetbean caterpillars, corn earworms, tobacco budworms, mole crickets, American cockroaches and honey bees.
通过草地贪夜蛾（Spodoptera frugiperda）幼虫中肠微粒体的混合功能氧化酶系统，联苯被羟基化为4-羟基联苯。确定了测定该酶的最佳条件。微粒体联苯4-羟化酶活性在幼虫发育过程中增加，在预蛹期下降。发现化感物质（单萜、吲哚和黄酮）、药物（苯巴比妥和3-甲基胆蒽）和寄主植物可诱导该羟化酶。还发现该酶在其他物种中也相当活跃，如豆天蛾、棉铃虫、烟草夜蛾、蝼蛄、美洲大蠊和蜜蜂。
