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Valproic acid increases gamma-aminobutyric acid in CSF of epileptic children.

作者信息

Löscher W, Siemes H

出版信息

Lancet. 1984 Jul 28;2(8396):225. doi: 10.1016/s0140-6736(84)90509-9.

DOI:10.1016/s0140-6736(84)90509-9
PMID:6146779
Abstract
摘要

相似文献

1
Valproic acid increases gamma-aminobutyric acid in CSF of epileptic children.丙戊酸可增加癫痫患儿脑脊液中的γ-氨基丁酸含量。
Lancet. 1984 Jul 28;2(8396):225. doi: 10.1016/s0140-6736(84)90509-9.
2
Cerebrospinal fluid gamma-aminobutyric acid levels in children with different types of epilepsy: effect of anticonvulsant treatment.不同类型癫痫患儿脑脊液中γ-氨基丁酸水平：抗惊厥治疗的影响
Epilepsia. 1985 Jul-Aug;26(4):314-9. doi: 10.1111/j.1528-1157.1985.tb05656.x.
3
Low CSF GABA concentration in children with febrile convulsions, untreated epilepsy, and meningitis.热性惊厥、未经治疗的癫痫和脑膜炎患儿脑脊液中γ-氨基丁酸（GABA）浓度较低。
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Neurophysiological and biochemical changes evoked by valproic acid in the central nervous system.
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GABA levels in cerebrospinal fluid of patients with epilepsy.癫痫患者脑脊液中的γ-氨基丁酸水平。
Folia Psychiatr Neurol Jpn. 1985;39(4):515-9. doi: 10.1111/j.1440-1819.1985.tb00805.x.
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Alteration of amino acid content of cerebrospinal fluid from patients with epilepsy.癫痫患者脑脊液氨基酸含量的改变。
Acta Neurol Scand. 1988 Dec;78(6):473-9. doi: 10.1111/j.1600-0404.1988.tb03690.x.
7
Low cerebrospinal fluid gamma-aminobutyric acid content in seizure patients.癫痫患者脑脊液中γ-氨基丁酸含量较低。
Neurology. 1979 Sep;29(9 Pt 1):1203-8. doi: 10.1212/wnl.29.9_part_1.1203.
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Dissimilar effects of lithium and valproic acid on GABA and glutamine concentrations in rat cerebrospinal fluid.
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Cerebrospinal fluid gamma-aminobutyric acid and glutamate values in dogs with epilepsy.患有癫痫的犬脑脊液中γ-氨基丁酸和谷氨酸的值。
Am J Vet Res. 1997 May;58(5):451-6.
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[Gamma-aminobutyric acid (GABA) and homovanillic acid (HVA) levels in the cerebrospinal fluid of patients with epilepsy].
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1
Dogs as a Natural Animal Model of Epilepsy.狗作为癫痫的天然动物模型。
Front Vet Sci. 2022 Jun 22;9:928009. doi: 10.3389/fvets.2022.928009. eCollection 2022.
2
Valproate disturbs the balance between branched and aromatic amino acids in rats.丙戊酸盐会扰乱大鼠体内支链氨基酸和芳香族氨基酸之间的平衡。
Neurotox Res. 2014 May;25(4):358-68. doi: 10.1007/s12640-013-9441-0. Epub 2013 Nov 19.
3
Long-term valproate treatment increases brain neuropeptide Y expression and decreases seizure expression in a genetic rat model of absence epilepsy.
长期丙戊酸治疗增加了失神癫痫遗传大鼠模型的脑神经肽 Y 表达，并降低了癫痫发作的表达。
PLoS One. 2013 Sep 9;8(9):e73505. doi: 10.1371/journal.pone.0073505. eCollection 2013.
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Low threshold T-type calcium channels as targets for novel epilepsy treatments.低阈值T型钙通道作为新型癫痫治疗的靶点。
Br J Clin Pharmacol. 2014 May;77(5):729-39. doi: 10.1111/bcp.12205.
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Epilepsy and medication effects on the pattern visual evoked potential.癫痫及药物对图形视觉诱发电位的影响
Doc Ophthalmol. 2005 Jan;110(1):121-31. doi: 10.1007/s10633-005-7350-0.
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Increased sensitivity to the anticonvulsant effect of valproate in aging BN/BiRij rats.衰老的BN/BiRij大鼠对丙戊酸盐抗惊厥作用的敏感性增加。
Pharm Res. 1993 Jul;10(7):1046-51. doi: 10.1023/a:1018975025417.
7
Differential effects of vigabatrin, gamma-acetylenic GABA, aminooxyacetic acid, and valproate on levels of various amino acids in rat brain regions and plasma.氨己烯酸、γ-乙炔基 GABA、氨基氧乙酸和丙戊酸盐对大鼠脑区和血浆中各种氨基酸水平的不同影响。
Naunyn Schmiedebergs Arch Pharmacol. 1994 Mar;349(3):270-8. doi: 10.1007/BF00169293.
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Effects of the antiepileptic drug valproate on metabolism and function of inhibitory and excitatory amino acids in the brain.抗癫痫药物丙戊酸盐对大脑中抑制性和兴奋性氨基酸代谢及功能的影响。
Neurochem Res. 1993 Apr;18(4):485-502. doi: 10.1007/BF00967253.
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The effect of sodium valproate on luteinizing hormone secretion in women with polycystic ovary disease.
J Endocrinol Invest. 1995 Feb;18(2):104-8. doi: 10.1007/BF03349709.
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Antiepileptic drugs and mechanisms of epileptogenesis. A review.抗癫痫药物与癫痫发生机制。综述。
Ital J Neurol Sci. 1995 May;16(4):217-22. doi: 10.1007/BF02282992.