日本婴儿神经母细胞瘤大规模筛查。大规模筛查研究组中期报告。
Mass screening for neuroblastoma in infants in Japan. Interim report of a mass screening study group.
作者信息
Sawada T, Hirayama M, Nakata T, Takeda T, Takasugi N, Mori T, Maeda K, Koide R, Hanawa Y, Tsunoda A
出版信息
Lancet. 1984 Aug 4;2(8397):271-3. doi: 10.1016/s0140-6736(84)90311-8.
A mass screening system for the early detection by means of a vanillylmandelic acid test of neuroblastoma in 6-month-old infants in Japan has been developed in eight districts. 16 of the 281 939 infants screened by this test had neuroblastoma, equivalent to a very high incidence of 1 in 17 621. 15 of the 16 children with neuroblastoma are alive; the other child died 1 month after surgery. This mass screening system for neuroblastoma used in infancy can help to improve prognosis in infants with this malignant disorder.
日本已在八个地区开发了一种大规模筛查系统，用于通过香草扁桃酸试验对6个月大婴儿进行神经母细胞瘤的早期检测。通过该测试筛查的281939名婴儿中，有16名患有神经母细胞瘤，发病率高达1/17621。16名神经母细胞瘤患儿中有15名存活；另一名患儿术后1个月死亡。这种用于婴儿期的神经母细胞瘤大规模筛查系统有助于改善患有这种恶性疾病的婴儿的预后。
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