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两种膜转运ATP酶(大肠杆菌的Kdp - ATP酶和肌质网的Ca2 + - ATP酶)之间的序列同源性。

Sequence homology between two membrane transport ATPases, the Kdp-ATPase of Escherichia coli and the Ca2+-ATPase of sarcoplasmic reticulum.

作者信息

Hesse J E, Wieczorek L, Altendorf K, Reicin A S, Dorus E, Epstein W

出版信息

Proc Natl Acad Sci U S A. 1984 Aug;81(15):4746-50. doi: 10.1073/pnas.81.15.4746.

DOI:10.1073/pnas.81.15.4746
PMID:6146979
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC391567/
Abstract

We have determined the DNA sequences of the genes encoding the three structural proteins of the Kdp-ATPase, an ATP-driven potassium transport system of Escherichia coli. Regions of the predicted amino acid sequence of KdpB, the phosphorylated protein of the system, are homologous to regions of the Ca2+-ATPase of rabbit sarcoplasmic reticulum. The phosphorylated aspartate residue of the latter is within a region of homology.

摘要

我们已经确定了编码Kdp - ATP酶三种结构蛋白的基因的DNA序列,Kdp - ATP酶是大肠杆菌的一种由ATP驱动的钾转运系统。该系统的磷酸化蛋白KdpB的预测氨基酸序列区域与兔肌浆网Ca2 + - ATP酶的区域同源。后者的磷酸化天冬氨酸残基位于同源区域内。

相似文献

1
Sequence homology between two membrane transport ATPases, the Kdp-ATPase of Escherichia coli and the Ca2+-ATPase of sarcoplasmic reticulum.两种膜转运ATP酶(大肠杆菌的Kdp - ATP酶和肌质网的Ca2 + - ATP酶)之间的序列同源性。
Proc Natl Acad Sci U S A. 1984 Aug;81(15):4746-50. doi: 10.1073/pnas.81.15.4746.
2
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Cloning of the K+-ATPase of Streptococcus faecalis. Structural and evolutionary implications of its homology to the KdpB-protein of Escherichia coli.粪肠球菌钾离子-ATP酶的克隆。其与大肠杆菌KdpB蛋白同源性的结构及进化意义。
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本文引用的文献

1
Partial characterization of a phosphorylated intermediate associated with the plasma membrane ATPase of corn roots.玉米根质膜 ATP 酶磷酸化中间产物的部分特性
Proc Natl Acad Sci U S A. 1982 Nov;79(22):6922-6. doi: 10.1073/pnas.79.22.6922.
2
Similar amino acid sequences: chance or common ancestry?相似的氨基酸序列:偶然因素还是共同祖先?
Science. 1981 Oct 9;214(4517):149-59. doi: 10.1126/science.7280687.
3
A simple method for displaying the hydropathic character of a protein.一种展示蛋白质亲水性特征的简单方法。
J Mol Biol. 1982 May 5;157(1):105-32. doi: 10.1016/0022-2836(82)90515-0.
4
Complete nucleotide sequence and identification of membrane components of the histidine transport operon of S. typhimurium.鼠伤寒沙门氏菌组氨酸转运操纵子的完整核苷酸序列及膜成分鉴定
Nature. 1982 Aug 19;298(5876):723-7. doi: 10.1038/298723a0.
5
Structure and function of the calcium pump protein of sarcoplasmic reticulum.肌浆网钙泵蛋白的结构与功能
Annu Rev Physiol. 1982;44:297-317. doi: 10.1146/annurev.ph.44.030182.001501.
6
The proton-translocating ATPase of the fungal plasma membrane.真菌质膜的质子转运ATP酶。
Biochim Biophys Acta. 1981 Dec 30;639(3-4):197-223. doi: 10.1016/0304-4173(81)90010-0.
7
Sequence of the lactose permease gene.乳糖通透酶基因序列。
Nature. 1980 Feb 7;283(5747):541-5. doi: 10.1038/283541a0.
8
Purification of the membrane-spanning tryptic peptides of the alpha polypeptide from sodium and potassium ion activated adenosinetriphosphatase labeled with 1-tritiospiro[adamantane-4,3'-diazirine].从用1-氚代螺[金刚烷-4,3'-二氮杂环丙烷]标记的钠钾离子激活的三磷酸腺苷酶中纯化α多肽的跨膜胰蛋白酶肽段。
Biochemistry. 1984 Feb 28;23(5):888-98. doi: 10.1021/bi00300a015.
9
The nucleotide sequence of the atp genes coding for the F0 subunits a, b, c and the F1 subunit delta of the membrane bound ATP synthase of Escherichia coli.编码大肠杆菌膜结合ATP合酶F0亚基a、b、c以及F1亚基δ的atp基因的核苷酸序列。
Mol Gen Genet. 1981;184(1):33-9. doi: 10.1007/BF00271191.
10
The atp operon: nucleotide sequence of the promoter and the genes for the membrane proteins, and the delta subunit of Escherichia coli ATP-synthase.ATP操纵子:大肠杆菌ATP合酶膜蛋白及δ亚基基因启动子的核苷酸序列
Nucleic Acids Res. 1981 Aug 25;9(16):3919-26. doi: 10.1093/nar/9.16.3919.