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编码大肠杆菌1型菌毛亚基的fimA基因。该蛋白质的核苷酸序列和一级结构。

The fimA gene encoding the type-1 fimbrial subunit of Escherichia coli. Nucleotide sequence and primary structure of the protein.

作者信息

Klemm P

出版信息

Eur J Biochem. 1984 Sep 3;143(2):395-9. doi: 10.1111/j.1432-1033.1984.tb08386.x.

DOI:10.1111/j.1432-1033.1984.tb08386.x
PMID:6147250
Abstract

The nucleotide sequence was determined of a region of 1450 base pairs encompassing the fimA gene for the subunit of type 1 fimbriae of Escherichia coli as well as flanking regions containing potential regulator sequences. The 'translated' protein contains a 23-residue signal peptide; the processed fimbrial subunit consists of 158 amino acid residues yielding a relative molecular mass of 15706. The elucidated sequence shows significant homology with those of other E. coli fimbrial proteins.

摘要

测定了一段1450个碱基对区域的核苷酸序列，该区域包含大肠杆菌1型菌毛亚基的fimA基因以及含有潜在调控序列的侧翼区域。“翻译”后的蛋白质含有一个23个残基的信号肽；加工后的菌毛亚基由158个氨基酸残基组成，相对分子质量为15706。所阐明的序列与其他大肠杆菌菌毛蛋白的序列具有显著同源性。

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