Simon B, Müller P, Dammann H G
Fortschr Med. 1984 Jul 12;102(25-26):683-7.
Peptic ulcers can be treated successfully with antisecretory drugs and drugs which have a protective effect. Thanks to their good tolerance and a form of administration acceptable to patients, the H2-receptor antagonists have won a leading position amongst the other ulcer therapeutics. It remains to be seen whether the substituted benzimidazoles will develop into a serious competitor. Until now the clinical experiences with the prostaglandins in the treatment of ulcers are not very encouraging.
消化性溃疡可用抗分泌药物和具有保护作用的药物成功治疗。由于H2受体拮抗剂耐受性良好且给药方式为患者所接受,它们在其他溃疡治疗药物中占据了领先地位。取代苯并咪唑类药物是否会成为一个强有力的竞争对手还有待观察。到目前为止,前列腺素用于治疗溃疡的临床经验并不十分令人鼓舞。