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[抗分泌及黏膜保护药物在消化性溃疡急性治疗中的应用。已批准溃疡药物及临床试验中药物的作用原理、愈合率和副作用综述]

[Antisecretory and mucosa-protecting drugs in the acute care of peptic ulcer. Review of action principles, healing rates and side effects of approved ulcer drugs and drugs under clinical trial].

作者信息

Simon B, Müller P, Dammann H G

出版信息

Fortschr Med. 1984 Jul 12;102(25-26):683-7.

PMID:6147304
Abstract

Peptic ulcers can be treated successfully with antisecretory drugs and drugs which have a protective effect. Thanks to their good tolerance and a form of administration acceptable to patients, the H2-receptor antagonists have won a leading position amongst the other ulcer therapeutics. It remains to be seen whether the substituted benzimidazoles will develop into a serious competitor. Until now the clinical experiences with the prostaglandins in the treatment of ulcers are not very encouraging.

摘要

消化性溃疡可用抗分泌药物和具有保护作用的药物成功治疗。由于H2受体拮抗剂耐受性良好且给药方式为患者所接受,它们在其他溃疡治疗药物中占据了领先地位。取代苯并咪唑类药物是否会成为一个强有力的竞争对手还有待观察。到目前为止,前列腺素用于治疗溃疡的临床经验并不十分令人鼓舞。

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