Gehanno P, Marche C, Deschamps V, Guedon C, Meyrier A, Boschi Laot M T
Ann Otolaryngol Chir Cervicofac. 1984;101(5):401-5.
Three cases are reported of necrotizing angiitis of otologic origin (one polyarteritis nodosa and two wegener's disease). Data in the published literature are reviewed and necrotizing angiitis classified. Two features resulting from this review are emphasized. Firstly, form the pathogenic point of view the fact that specific lesions were detected in the ear in one of these patients means that this localization may be a possible visceral manifestation, as are rhinologic and pulmonary lesions. Otologic sites may be an isolated, or in association, further type of pathogenic mechanism. From the practical point of view, any unexpected serous otitis in adults should suggest the need for an erythrocyte sedimentation test, very high values requiring investigation of etiology. This will avoid unnecessary medical and surgical treatments and the institution of immunosuppressant therapy active against all visceral lesions and the only effective means of treating the otitis. Early treatment could avoid the catastrophic prognosis observed short-term in the 3 cases reported.
报告了3例耳源性坏死性血管炎病例（1例结节性多动脉炎和2例韦格纳肉芽肿病）。对已发表文献中的数据进行了回顾，并对坏死性血管炎进行了分类。强调了此次回顾得出的两个特征。首先，从致病角度来看，在其中1例患者的耳部检测到特定病变这一事实意味着，这种定位可能是一种可能的内脏表现，就像鼻科和肺部病变一样。耳部部位可能是一种孤立的或相关的进一步致病机制类型。从实际角度来看，成人中任何意外的浆液性中耳炎都应提示需要进行红细胞沉降试验，极高的值需要对病因进行调查。这将避免不必要的药物和手术治疗以及针对所有内脏病变的免疫抑制治疗的实施，而免疫抑制治疗是治疗中耳炎的唯一有效手段。早期治疗可以避免在所报告的3例病例中短期内观察到的灾难性预后。
