Batár I
Int J Gynaecol Obstet. 1984 Jun;22(3):203-6. doi: 10.1016/0020-7292(84)90006-7.
In a retrospective study containing 2404 cases of IUD induced bleeding problems, the type and timing of bleeding as well as the types of conservative therapy were evaluated. The non-hormonal treatment (uterotonics, calcium, C- and K-vitamin etc.) proved to be significantly less effective (P less than 0.05) than the hormonal therapy (estrogen, gestagen and combined preparations). The rate of effectiveness was 80.1% and 86.7%, respectively. Because the effectiveness of the conservative therapy is 80%, even in the non-hormonal group, the IUD should be removed only if this treatment proves to be ineffective. Attention is drawn to the importance of routine colposcopic and cytological screening.
在一项包含2404例宫内节育器(IUD)所致出血问题的回顾性研究中,对出血的类型和时间以及保守治疗的类型进行了评估。结果证明,非激素治疗(宫缩剂、钙、维生素C和维生素K等)的效果明显低于激素治疗(雌激素、孕激素及联合制剂)(P<0.05)。有效率分别为80.1%和86.7%。由于保守治疗的有效率为80%,即使在非激素组,也只有在治疗无效时才应取出宫内节育器。强调了常规阴道镜检查和细胞学筛查的重要性。