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胆石症患者的基础血浆生长抑素

Basal plasma somatostatin in biliary stone patients.

作者信息

Schwille P O, Hanisch E, Engelhardt W, Scholz D

出版信息

Klin Wochenschr. 1984 Jun 15;62(12):595-7. doi: 10.1007/BF01728179.

DOI:10.1007/BF01728179
PMID:6148449
Abstract

We have searched for elevated basal plasma somatostatin in patients with documented cholelithiasis (n = 37) and compared the data with healthy control subjects (n = 27). Using an acidic assay system for measuring somatostatin in unprocessed plasma, we could not find deviations from normal values in biliary stone patients. Also basal blood levels of other islet cell hormones (insulin, glucagon) and minerals (calcium, magnesium) are unchanged. Further studies are needed to find out whether an abnormal response of plasma somatostatin to appropriate stimuli can play a role in the etiology of biliary stones.

摘要

我们对确诊为胆石症的患者(n = 37)进行了基础血浆生长抑素水平升高情况的研究,并将数据与健康对照受试者(n = 27)进行了比较。使用酸性检测系统测量未经处理血浆中的生长抑素,我们未发现胆石症患者的数值与正常值有偏差。其他胰岛细胞激素(胰岛素、胰高血糖素)和矿物质(钙、镁)的基础血液水平也未改变。需要进一步研究以确定血浆生长抑素对适当刺激的异常反应是否在胆石症的病因中起作用。

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本文引用的文献

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Changes in gallbladder motor function during the female cycle--a risk factor leading to gallstone formation?
Klin Wochenschr. 1982 Nov 2;60(21):1357-62. doi: 10.1007/BF01716215.
2
Somatostatinoma syndrome: does a clinical entity exist?生长抑素瘤综合征:是否存在一种临床实体?
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The role of somatostatin during the gastric phase of a meal.生长抑素在进餐胃期的作用。
Hepatogastroenterology. 1980 Jun;27(3):240-6.
9
Effects of test meal, intragastric nutrients, and intraduodenal bile on plasma concentrations of immunoreactive somatostatin and vasoactive intestinal peptide in dogs.试验餐、胃内营养物质及十二指肠内胆汁对犬血浆免疫反应性生长抑素和血管活性肠肽浓度的影响。
Gastroenterology. 1980 Nov;79(5 Pt 1):844-52.
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Coated charcoal immunoassay of insulin.胰岛素的包被炭免疫测定法。
J Clin Endocrinol Metab. 1965 Oct;25(10):1375-84. doi: 10.1210/jcem-25-10-1375.