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赫尔曼陆龟(Testudo hermanni Gmelin)大脑中的生长抑素。一项免疫组织化学定位研究。

Somatostatin in the brain of the turtle Testudo hermanni Gmelin. An immunohistochemical mapping study.

作者信息

Weindl A, Triepel J, Kuchling G

出版信息

Peptides. 1984;5 Suppl 1:91-100. doi: 10.1016/0196-9781(84)90268-7.

DOI:10.1016/0196-9781(84)90268-7
PMID:6148740
Abstract

An immunohistochemical mapping study in the brain and upper spinal cord of the turtle Testudo hermanni Gmelin revealed a wide distribution of somatostatin perikarya and fibres. Within the telencephalon, somatostatin perikarya are present in the anterior olfactory nucleus, in the medial, dorsomedial and dorsal cortex, in the pallial thickening, in the piriform cortex, paleostriatum augmentatum, in the dorsoventricular ridge, core nucleus of the dorsoventricular ridge, in area c and d, and in the amygdala. In the diencephalon, the periventricular nucleus of the hypothalamus contains many somatostatin perikarya. Cerebrospinal fluid contacting somatostatin perikarya of the infundibular nucleus terminate with club-like endings in the ventricular cavity. Some somatostatin perikarya are present in the nu. reuniens of the thalamus and in the lateral habenular nucleus of the epithalamus. Within the mesencephalon somatostatin perikarya are located in the interpeduncular nucleus, area tegmentalis ventralis and in the nu. reticularis isthmi. In the rhombencephalon, somatostatin perikarya are encountered in the nu. raphe superior, nu. reticularis magnus, periventricular grey matter, bed nucleus of the fasciculus longitudinalis medialis and in the nu. solitarius-vagus complex. Somatostatin fibres form a circular band in the olfactory bulb. In the telencephalon, dense aggregations of somatostatin fibres are present in the anterior olfactory nucleus, in the pallial thickening, in the parahippocampal gyrus, cortex medialis, dorsomedialis, dorsalis and piriformis, in the dorsal ventricular ridge, paleostriatum augmentatum, area c and d, in the septum, nu. diagonalis of Broca, in the amygdala and in the anterior commissure. In the diencephalon, somatostatin fibres terminate at the vessels of the organum vasculosum of the lamina terminalis. A dense band of somatostatin fibres surrounds the rostral third ventricle. Somatostatin fibres terminate in the infundibulum at portal capillaries, and in the neural lobe. Somatostatin fibres are found in the periventricular, ventromedial and lateral nucleus of the hypothalamus. In the thalamus, the area triangularis, the dorsomedial and dorsolateral area and the nu. reuniens contain somatostatin fibres. Somatostatin fibres are very dense in the lateral habenular nucleus. At the mesencephalic level, somatostatin fibres are found in the pretectal nucleus, in the deep layers of the tectum, in the nu. tori semicircularis lateralis, in the interpeduncular nucleus, area tegmentalis ventralis, nu. ruber, substantia nigra and periventricular grey.(ABSTRACT TRUNCATED AT 400 WORDS)

摘要

对赫尔曼陆龟(Testudo hermanni Gmelin)大脑和上脊髓进行的免疫组织化学定位研究显示,生长抑素的胞体和纤维分布广泛。在端脑内,生长抑素胞体存在于前嗅核、内侧、背内侧和背侧皮质、皮质增厚区、梨状皮质、增大型旧纹状体、背侧脑室嵴、背侧脑室嵴核心核、c区和d区以及杏仁核。在间脑,下丘脑室周核含有许多生长抑素胞体。与脑脊液接触的漏斗核生长抑素胞体以棒状终末终止于脑室腔。丘脑的 reuniens核和上丘脑的外侧缰核也有一些生长抑素胞体。在中脑内,生长抑素胞体位于脚间核、腹侧被盖区和峡部网状核。在菱脑,生长抑素胞体见于上缝际核、巨网状核、室周灰质、内侧纵束终床核和孤束 - 迷走复合体。生长抑素纤维在嗅球形成一个环状带。在端脑,生长抑素纤维密集聚集于前嗅核、皮质增厚区、海马旁回、内侧皮质、背内侧皮质、背侧皮质和梨状皮质、背侧脑室嵴、增大型旧纹状体、c区和d区、隔区、布洛卡斜角带核、杏仁核和前连合。在间脑,生长抑素纤维终止于终板血管器的血管。一条生长抑素纤维致密带环绕第三脑室前部。生长抑素纤维在漏斗处终止于门脉毛细血管以及神经叶。生长抑素纤维见于下丘脑的室周核、腹内侧核和外侧核。在丘脑,三角区、背内侧和背外侧区以及reuniens核含有生长抑素纤维。外侧缰核内的生长抑素纤维非常密集。在中脑水平,生长抑素纤维见于顶盖前核、顶盖深层、外侧半环形核、脚间核、腹侧被盖区、红核、黑质和室周灰质。(摘要截于400字)

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