Vinarová E, Vinar O, Kalvach Z
Biol Psychiatry. 1984 Aug;19(8):1265-8.
There is indirect evidence that smoking induces higher enzymatic activity which accelerates the metabolism of many drugs. This influence is inferred from the frequency and magnitude of drug side effects. We could demonstrate that smokers need higher doses of neuroleptic drugs than nonsmokers.
有间接证据表明，吸烟会诱导更高的酶活性，从而加速许多药物的代谢。这种影响是从药物副作用的频率和严重程度推断出来的。我们可以证明，吸烟者比不吸烟者需要更高剂量的抗精神病药物。
