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难治性恶性腹水患者的LeVeen分流术

LeVeen shunts in patients with intractable malignant ascites.

作者信息

Kudsk K, Fabian T C, Minton J P

出版信息

J Surg Oncol. 1980;13(1):61-6. doi: 10.1002/jso.2930130110.

Abstract

LeVeen shunts were placed in ten patients bedridden with intractable malignant ascites in order to improve comfort and ambulation. The procedure was done with local anesthesia and mild sedation in all but one patient. Mild prolongations in clotting studies and hypokalemia were noted in several patients, but severe complications were few: a bleeding diathesis in a jaundiced patient, and venous disease in two. Six of the ten had excellent clinical response and were able to undergo therapy impossible in the presence of massive ascites. Two had moderate benefit but remained bedridden. Two patients gained no relief. Elevated bilirubin and inability to tolerate rapid increase in vascular volume and excrete the fluid load contraindicate the procedure, but the LeVeen shunt appears to be of significant clinical benefit in selected cases of malignant ascites.

摘要

为了提高舒适度和活动能力,对10例因顽固性恶性腹水而卧床的患者置入了LeVeen分流管。除1例患者外,其余均在局部麻醉和轻度镇静下进行该手术。部分患者凝血检查轻度延长及出现低钾血症,但严重并发症较少:1例黄疸患者出现出血倾向,2例出现静脉疾病。10例中有6例临床反应良好,能够接受在大量腹水存在时无法进行的治疗。2例有中度获益,但仍需卧床。2例患者未获缓解。胆红素升高以及无法耐受血容量快速增加和排出液体负荷是该手术的禁忌证,但LeVeen分流管在某些恶性腹水病例中似乎具有显著的临床益处。

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