Insley J
J R Coll Physicians Lond. 1980 Apr;14(2):100-5.
We are still in the early days as far as antenatal diagnosis of fetal disease and abnormality are concerned. All of the techniques show a high degree of accuracy if used in the correct circumstances but, apart from the use of maternal blood to assess the Rhesus status and screen for neural tube defects and amniocentesis to search for age-dependent mongolism, present techniques are too cumbersome, inaccurate and dangerous to be offered as routine antenatal tests. The rapid development in ultrasound equipment and expertise and the recent advances in fetal blood sampling and biochemistry suggest that there will be continued and rapid expansion within the field.
就胎儿疾病和异常的产前诊断而言，我们仍处于早期阶段。如果在正确的情况下使用，所有这些技术都显示出高度的准确性，但是，除了使用母体血液来评估恒河猴血型状态、筛查神经管缺陷以及使用羊膜穿刺术来检测与年龄相关的唐氏综合征外，目前的技术过于繁琐、不准确且危险，无法作为常规产前检查提供。超声设备和专业知识的迅速发展以及胎儿血液采样和生物化学方面的最新进展表明，该领域将持续快速扩展。
