Jamieson M P, Rees P G, Stark J, de Leval M
Thorac Cardiovasc Surg. 1980 Feb;28(1):48-50. doi: 10.1055/s-2007-1022050.
A 13-year-old girl presented with infective endocarditis of the tricuspid valve related to a residual ventricular septal defect. Antibiotic therapy produced a satisfactory initial improvement, however, subsequent deterioration with uncontrolled infection, in spite of alterations in the antibiotic regime, necessitated surgical intervention. Because the endocarditis was localized to the septal leaflet, management by excision of this leaflet and annuloplasty was possible and resulted in a rapid and sustained clinical improvement with no evidence of significant residual valvar incompetence. The medical management of infective endocarditis requires bacteriological assessment to ensure that the drugs and dosages selected are appropriate and adequate for the causative organism. Early operation may be required for uncontrolled infection or cardiac decompensation; in tricuspid endocarditis secondary to a ventricular septal defect, the operation described permits removal of infective tissue while retaining valvar competence.
一名13岁女孩因残余室间隔缺损并发三尖瓣感染性心内膜炎。抗生素治疗初期取得了令人满意的改善,但尽管调整了抗生素治疗方案,随后感染仍无法控制而病情恶化,因此需要进行手术干预。由于心内膜炎局限于隔叶,可行该叶切除及瓣环成形术,术后临床症状迅速且持续改善,无明显残余瓣膜关闭不全的迹象。感染性心内膜炎的药物治疗需要进行细菌学评估,以确保所选药物和剂量对病原体合适且足够。对于无法控制的感染或心脏失代偿可能需要早期手术;在室间隔缺损继发的三尖瓣心内膜炎中,所述手术可在保留瓣膜功能的同时清除感染组织。