人脑肿瘤染色质蛋白的遗传学方面。

A genetic aspect of chromatin proteins of human brain tumors.

作者信息

Fujii K, Yonemasu Y, Kitamura K, Tsubota Y

出版信息

J Neurol. 1980;223(1):23-34. doi: 10.1007/BF00313137.

Abstract

Electrophoretic analysis of chromatin proteins was performed on rat and human tissues. Species and organ specific patterns were demonstrated in them. Twenty cases of human brain tumours were also analyzed and each tumor had typical phoretic patterns of chromatin. Proteins obtained from histologically similar tumors display similar electrophoretic patterns. As to the ratio of chromatin protein to DNA, no apparent differences between benign and malignant human brain tumors were observed.

摘要

对大鼠和人类组织进行了染色质蛋白的电泳分析。在这些组织中显示出了物种和器官特异性模式。还分析了20例人类脑肿瘤，每个肿瘤都有典型的染色质电泳模式。从组织学上相似的肿瘤中获得的蛋白质显示出相似的电泳模式。至于染色质蛋白与DNA的比例，在良性和恶性人类脑肿瘤之间未观察到明显差异。