Stegmann T, Daniel W, Bellmann L, Trenkler G, Oelert H, Borst H G
Thorac Cardiovasc Surg. 1980 Apr;28(2):141-9. doi: 10.1055/s-2007-1022065.
In 74 mongrel dogs 0.02 ml air/kg of body weight was injected into the left anterior descending coronary artery (LAD). Forty-three dogs were studied without (group I) and 31 with (group II) extracorporeal circulation (ECC). Time course and extent of myocardial ischemia were assessed by continous thermographic measurements as well as by fluorescence techniques. Coronary air embolism resulted in an immediate decrease of myocardial temperature associated with transmural ischemia. In 31 surviving dogs (72%) of group I this phenomenon was fully reversible within 8.7 minutes as compared with 5.4 minutes in 100% of the surviving dogs from group II. No postembolic death occurred in the group II animals. In group II the postembolic temperature decrease was significantly less than that in group I, and, in addition, the myocardial area involved was significantly smaller. The results indicate that the extent of myocardial ischemia following coronary air embolism and its time course can be well-documented by means of thermocardiography; using extracorporeal circulation survival can be improved and myocardial damage minimized.
在74只杂种犬中，将0.02毫升/千克体重的空气注入左冠状动脉前降支（LAD）。对43只未使用体外循环（ECC）的犬（I组）和31只使用体外循环的犬（II组）进行了研究。通过连续热成像测量以及荧光技术评估心肌缺血的时间进程和范围。冠状动脉空气栓塞导致心肌温度立即下降，并伴有透壁性缺血。I组31只存活犬（72%）中，这种现象在8.7分钟内完全可逆，而II组100%存活犬的这一现象在5.4分钟内完全可逆。II组动物未发生栓塞后死亡。II组栓塞后温度下降明显小于I组，此外，受累心肌面积也明显较小。结果表明，通过热心动图可以很好地记录冠状动脉空气栓塞后心肌缺血的程度及其时间进程；使用体外循环可提高存活率并使心肌损伤最小化。
