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血浆代用品对大鼠组织儿茶酚胺浓度的影响。

Influence of plasma substitutes on the concentration of tissue catecholamines in rats.

作者信息

Szymańska-Kosmala M, Filczewski M

出版信息

Acta Physiol Pol. 1980 Mar-Apr;31(2):167-77.

PMID:6156573
Abstract

The concentration of catecholamines was determined in the brain, heart and adrenals in normovolaemic and hypovolaemic rats after reinfusion of the lost blood and after infusion of equivalent volumes of plasma substitutes (dextran and modified gelatins). After infusion of these preparations in normovolaemic rats noradrenaline concentration increased significantly in the myocardium. It was found also that restoration of normal blood volume by infusion of plasma substitutes prevented changes in catecholamine concentrations induced by hypovolaemia in the brain but not in the adrenals.

摘要

在失血性正常血容量和低血容量大鼠中,在回输丢失血液以及输注等量血浆代用品(右旋糖酐和改良明胶)后,测定脑、心脏和肾上腺中儿茶酚胺的浓度。在正常血容量大鼠中输注这些制剂后,心肌中去甲肾上腺素浓度显著增加。还发现,通过输注血浆代用品恢复正常血容量可防止低血容量引起的脑内儿茶酚胺浓度变化,但不能防止肾上腺内的变化。

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