De La Pierre M, Sategna Guidetti C, Pera A
Minerva Med. 1976 Sep 19;67(43):2787-800.
A personal series of 28 cases of malabsorption with villopathy (22 Gee, 1 Whipple, 1 alpha-chain, 1 hypogammaglobulinaemia, 3 not yet diagnosed) is presented. The response to a gluten-free diet is the essential clue to diagnosis. Where sensitivity is not found, diagnosis becomes difficult and requires careful immunological, histopathological and parasitological investigation, which is not always conclusive. The main features of the series are indicated, along with the criteria employed in the diagnosis of some unusual forms.
本文报告了一组28例伴有绒毛病变的吸收不良病例(22例乳糜泻、1例惠普尔病、1例α-链病、1例低丙种球蛋白血症、3例尚未确诊)。对无麸质饮食的反应是诊断的关键线索。若未发现敏感性,诊断则变得困难,需要进行仔细的免疫学、组织病理学和寄生虫学检查,但这些检查并非总能得出结论。文中指出了该病例系列的主要特征,以及诊断某些罕见类型所采用的标准。