Plesnicar S, Sumi-Kriznik T, Golouh R
Isr J Med Sci. 1975 Aug;11(8):832-7.
Clinical, immunochemical and pathological studies were performed in a 27-year-old male who presented with abdominal pain, the malabsorption syndrome, and marked weight loss. Immunoelectrophoretic studies revealed alpha-heavy chains in the patient's serum, urine and intestinal juice. Treatment with cyclophosphamide and corticosteroids produced an improvement in the patient's condition and he survived for 18 months after the onset of symptoms. Autopsy revealed a malignant lymphoma of mixed histiocytic-lymphocytic type involving mainly the mesenteric lymph nodes, but also affecting the jejunal mucosa, liver, spleen and extraabdominal lymph nodes. This is the first case of abdominal lymphoma with alpha-heavy chain disease to be reported from Yugoslavia.
对一名27岁男性进行了临床、免疫化学和病理学研究，该患者出现腹痛、吸收不良综合征和显著体重减轻。免疫电泳研究显示患者血清、尿液和肠液中存在α重链。环磷酰胺和皮质类固醇治疗使患者病情有所改善，症状出现后存活了18个月。尸检显示为混合组织细胞-淋巴细胞型恶性淋巴瘤，主要累及肠系膜淋巴结，但也影响空肠黏膜、肝脏、脾脏和腹部外淋巴结。这是南斯拉夫报道的首例伴有α重链病的腹部淋巴瘤病例。
