Neurochemical changes in Creutzfeldt-Jakob disease.
作者信息
Federico A, Annunziata P, Malentacchi G
出版信息
J Neurol. 1980;223(2):135-46. doi: 10.1007/BF00313176.
PMID:6157003
Abstract
A biochemical study of a case affected by Creutzfeldt-Jakob disease is reported. Changes were found in soluble and insoluble proteins, glycoproteins and mucopolysaccharides and in total lipids, glycolipids, phospholipids and gangliosides. Also CNPase, choline acetyltransferase, 5'-nucleotidase and several glycosidases have an altered activity. All these data give a complete neurochemical pattern of the changes underlying the morphological and functional alterations in this disease.
摘要
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