[Changes in the immunological components of the blood during balneotherapy in patients with rheumatoid arthritis].

The changes of the immunoglobulin G, the C-reactive protein and the acid alpha 1-glycoprotein which were observed under spa therapy in patients with rheumatoid arthritis. In these cases was shown that these parameters undergo regulative influences which in typical relationship to the initial tissue lead to a cross-over-phenomenon with demarcation of a regulatory zero- (or normal) region. Here patients with rheumatoid arthritis show the tendency to maintain a slightly increased defensive condition under the cure. On the basis of a narrowing of the dispersion of the immune components to the end of the cure compared with the beginning of the cure is concluded that the changes of defensive components to the blood which are to be observed in different initial values are not only based on the endogenic rhythmicity but partly also on the effects of the spa therapy.