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阿片受体经历轴浆运输。

Opioid receptors undergo axonal flow.

作者信息

Young W S, Wamsley J K, Zarbin M A, Kuhar M J

出版信息

Science. 1980 Oct 3;210(4465):76-8. doi: 10.1126/science.6158097.

DOI:10.1126/science.6158097
PMID:6158097
Abstract

Previous studies have indicated the presence of opiate receptors on axons of the rat vagus nerve and on other small diameter fibers. In examinations of the effect of ligation on the distribution of receptors in the vagus nerve by in vitro labeling light microscopic autoradiography, a large buildup of receptors was found proximal to the ligature. This result indicates an axonal flow of receptors.

摘要

先前的研究表明,大鼠迷走神经轴突和其他小直径纤维上存在阿片受体。通过体外标记光镜放射自显影检查结扎对迷走神经中受体分布的影响时,发现结扎近端有大量受体聚集。这一结果表明受体存在轴突运输。

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