Neville A M
Arch Gynecol. 1980;229(4):311-23. doi: 10.1007/BF02108582.
Alphafetoprotein is at present the only 'antigen' of proved clinical value in gynaecological neoplasia. Its synthesis and release by a particular type of germ cell tumour (yolk sac, endodermal sinus tumour) present alone or as part of a teratoma approaches many of the essential criteria of a utopian tumour marker. Unfortunately, none of the other recognised 'antigens' expressed and/or released by gynaecological tumours and which have been adequately assessed in the clinical situation, seem to represent laboratory adjuncts essential for adequate patient care at present. Further research is needed to define other factors if this approach to improving diagnosis and management is to succeed.
甲胎蛋白是目前在妇科肿瘤中唯一已证实具有临床价值的“抗原”。它由特定类型的生殖细胞肿瘤（卵黄囊瘤、内胚窦瘤）单独合成并释放，或作为畸胎瘤的一部分，接近理想肿瘤标志物的许多基本标准。不幸的是，妇科肿瘤表达和/或释放的其他已被认可的“抗原”，且在临床情况下已得到充分评估，但目前似乎都不代表对患者进行充分护理所必需的实验室辅助手段。如果要通过这种方法成功改善诊断和治疗，还需要进一步研究来确定其他因素。
