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[慢性粒细胞增多症中中性粒细胞的吞噬活性(摄取及杀菌活性)]

[The phagocytic activity (ingestion and bactericidal activity) of neutrophil leukocytes in chronic myelosis].

作者信息

Jaworkowsky L, Shilevitsch A, Priedniece E, Grant H

出版信息

Folia Haematol Int Mag Klin Morphol Blutforsch. 1980;107(2):213-20.

PMID:6159261
Abstract

The paper deals with the results obtained by investigating the function of phagocytes (ingestion and bactericidity) in germs of a stem of staphylococcus aureus 209 and escherichia coli 0-III of mature neutrophilic granulocytes in 30 patients with chronic, not-lymphocytic leukaemia. The ingestion corresponded to the norm. Bactericidity towards the germs of staphylococcus aureus was statistically significant decreased, viz. it was retarded as well as diminished. In certain patients this deviation from the norm found a particularly strong expression, which became evident in clinical appearances. As it was to be expected, no interconnection could be detected between the activity of alkaline granulocytic phosphatase and the function of phagocytosis.

摘要

本文探讨了对30例慢性非淋巴细胞白血病患者成熟中性粒细胞吞噬细胞功能(摄取和杀菌能力)进行研究的结果,研究对象为金黄色葡萄球菌209株和大肠杆菌0-III株。摄取功能正常。对金黄色葡萄球菌菌株的杀菌能力在统计学上显著降低,即杀菌作用延迟且减弱。在某些患者中,这种与正常情况的偏差表现得尤为明显,并在临床表现中显现出来。正如预期的那样,未检测到碱性粒细胞磷酸酶活性与吞噬功能之间存在关联。

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