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脑梗死患者的癫痫

Epilepsy in patients with cerebral infarcts.

作者信息

de Reuck J, Krahel N, Sieben G, Orban L, de Coster W, vander Eecken H

出版信息

J Neurol. 1980;224(2):101-9. doi: 10.1007/BF00313348.

Abstract

Out of series of 240 patients, with proved cerebral infarcts at necropsy, 14 with a clinical history of epilepsy were selected. The possible etiology of seizures was analyzed by comparing the clinical and pathological data. It appeared from this series that epileptic spells, preceding for years the occurrence of a stroke, were due to other causes than to cerebrovascular insufficiency. It was also difficult to separate apoplectic seizures from those occurring due to scar formation after a cerebral infarct, as postapoplectic epilepsy was induced either by the occurrence of a new stroke or by hemodynamic disturbances. Severe generalized or local hemodynamic and metabolic disturbances were also noted in cases of convulsions resulting from a cerebral infarct.

摘要

在尸检证实为脑梗死的240例患者中,挑选出14例有癫痫病史的患者。通过比较临床和病理数据来分析癫痫发作的可能病因。从该系列病例来看,在中风发生前数年出现的癫痫发作是由脑血管功能不全以外的其他原因引起的。此外,由于中风后癫痫是由新的中风发作或血流动力学紊乱诱发的,因此很难将中风后癫痫发作与脑梗死形成瘢痕后发生的癫痫发作区分开来。在脑梗死引起惊厥的病例中,还发现了严重的全身性或局部血流动力学和代谢紊乱。

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