Henrichs I, Teller W M
Eur J Pediatr. 1980 Oct;135(1):3-11. doi: 10.1007/BF00445886.
Gastrointestinal hormones (GI hormones) have received growing interest in endocrinology, gastroenterology and neuroendocrinology. Because of new methodological techniques, they can be measured in plasma and therefore be related to different pathophysiological conditions. In childhood, our present knowledge is as yet limited to the physiological rôle of gastrin at different ages and in some diseases (gastrinoma; Verner-Morrison syndrome) caused by humoral dysfunction. The present review relates the clinical important GI hormones to chemically classified families. The diagnostic value of determining endogenous hormone concentration in plasma and the validity of function tests carried out by administration of exogenous hormones are pointed out. Particular emphasis is given to the trophic action of GI hormones in the development and function of the gastrointestinal tract during childhood. More speculatively, GI hormones are involved in the complex function of the central nervous system, thus making food intake a trophotropic action in a broader sense.
胃肠激素在内分泌学、胃肠病学和神经内分泌学领域受到越来越多的关注。由于新的方法技术，它们可以在血浆中被检测到，因此与不同的病理生理状况相关。在儿童时期，我们目前的知识仅限于胃泌素在不同年龄段以及某些由体液功能障碍引起的疾病（胃泌素瘤；韦纳 - 莫里森综合征）中的生理作用。本综述将临床上重要的胃肠激素与化学分类的家族联系起来。指出了测定血浆中内源性激素浓度的诊断价值以及通过给予外源性激素进行功能测试的有效性。特别强调了胃肠激素在儿童时期胃肠道发育和功能中的营养作用。更具推测性的是，胃肠激素参与中枢神经系统的复杂功能，从而使食物摄入在更广泛的意义上成为一种促营养作用。
