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泌尿生殖道原发性局限性淀粉样变性:11例免疫组织化学研究

Primary localized amyloidosis of the genitourinary tract: immunohistochemical study on eleven cases.

作者信息

Fujihara S, Glenner G G

出版信息

Lab Invest. 1981 Jan;44(1):55-60.

PMID:6161276
Abstract

Eleven cases of primary localized amyloidosis of the genitourinary tract were studied using the unlabeled immunoperoxidase method in combination with specific antisera against different chemical types of amyloid fibril proteins (AA,A lambda, and A kappa). Nine of these were shown to have A lambda antigenic fibril determinants, suggesting that the fibrils of most, if not all, of these cases are of immunocytic origin.

摘要

使用未标记免疫过氧化物酶法结合针对不同化学类型淀粉样原纤维蛋白(AA、Aλ和Aκ)的特异性抗血清,对11例原发性局限性泌尿生殖道淀粉样变性病例进行了研究。其中9例显示具有Aλ抗原性原纤维决定簇,这表明这些病例中大多数(如果不是全部)的原纤维起源于免疫细胞。

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