Sharma Richa, George Virgilio V
Richa Sharma, Virgilio V George, Department of General Surgery, School of Medicine, Indiana University, Indianapolis, IN 46202, United States.
World J Gastroenterol. 2015 Jan 28;21(4):1324-8. doi: 10.3748/wjg.v21.i4.1324.
Localized amyloidosis is characterized by amyloid protein deposition restricted to one organ or tissue without systemic involvement. Gastrointestinal manifestations of localized amyloidoma are unusual, which makes amyloidoma restricted to the rectum a very rare diagnosis requiring a high index of suspicion. We present a rare account for rectal amyloidoma with an unusual presentation of obstructive symptoms and its treatment using a sophisticated surgical modality, transanal endoscopic microsurgery (TEM), which resulted in complete excision of the lesion without hospitalization and complications. The successful treatment for this rectal amyloidoma using TEM emphasizes the need to broaden its application in the treatment of various rectal lesions while preserving organ function and decreasing recurrence.
局限性淀粉样变性的特征是淀粉样蛋白沉积局限于一个器官或组织，无全身受累。局限性淀粉样瘤的胃肠道表现并不常见，这使得局限于直肠的淀粉样瘤成为一种非常罕见的诊断，需要高度怀疑。我们报告一例罕见的直肠淀粉样瘤病例，其表现为不寻常的梗阻症状，并采用一种先进的手术方式——经肛门内镜显微手术（TEM）进行治疗，该手术成功完整切除病变，且无需住院，无并发症发生。使用TEM成功治疗该直肠淀粉样瘤强调了在保留器官功能和降低复发率的同时，扩大其在各种直肠病变治疗中应用的必要性。
