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PMFV和D型MPMV逆转录病毒结构蛋白p10 - 12上的共同抗原决定簇。

Common antigenic determinants on structural proteins p10--12 of PMFV and MPMV type D retroviruses.

作者信息

Voevodin A F, Wunderlich V, Denner J, Bierwolf D, Lapin B A

出版信息

Neoplasma. 1980;27(3):225-8.

PMID:6161313
Abstract

PMFV, a type D retrovirus isolated from a malignant human embryo cell line, was compared with Mason-Pfizer monkey virus (MPMV) in a sensitive tannic acid enhanced indirect immunodiffusion test. In addition to the previously shown common antigens, both viruses contain identical group-specific antigenic determinants on their p 10--12 as demonstrated with a specific p 10--12 MPMV test system. Interspecies mammalian type C virus antigens were not detected in highly concentrated PMFV preparations.

摘要

PMFV是一种从恶性人胚胎细胞系中分离出的D型逆转录病毒,在一项灵敏的单宁酸增强间接免疫扩散试验中,将其与梅森- Pfizer猴病毒(MPMV)进行了比较。除了先前显示的共同抗原外,如用特异性MPMV p 10 - 12检测系统所证实的,两种病毒在其p 10 - 12上都含有相同的群特异性抗原决定簇。在高浓度的PMFV制剂中未检测到种间哺乳动物C型病毒抗原。

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