Frank G, Klein H, Bednarska E, Gahl K, Flohr E, Trieb G, Borst H G
Thorac Cardiovasc Surg. 1980 Dec;28(6):423-7. doi: 10.1055/s-2007-1022444.
Although left ventricular aneurysmectomy (LVA) is a common surgical procedure, the late functional and hemodynamic results have not been well defined. This presentation describes our results with LVA in 135 patients operated between 1969 and 1979. Associated procedures were performed in 57 (42%) including coronary bypass grafting in 50, valve replacement in 5, closure of ventricular septal defect in 2, or combinations of these in 3 patients. One hundred four of the 122 hospital survivors were followed from 2 to 107 months (mean = 37 months). There were 13 hospital deaths (9.6%), 12 late deaths (9.8%) and an actuarial 5-year survival rate of 77%. Clinical improvement of preoperative heart failure occurred in 82%, and of angina in 70%. Only 33 patients (30%) returned to normal work. Bicycle exercise testing in 70 patients showed normal working capacity in 41 (59%). Recatheterization in 49 patients showed no significant changes in left ventricular end-diastolic pressure or cardiac index, and a borderline reduction of the total ejection fraction. Ventricular arrhythmias were detected by long-term ECG in 70% of all patients after surgery. Of those with preoperative life-threatening arrhythmias, rhythm improvement was noted in 50%, but only 2 of 13 patients were free of arrhythmias after operation. This study demonstrates a greater frequency of postoperative symptomatic and functional improvement as compared to hemodynamic and ECG improvement. Ventricular tachyarrhythmias originating from post-infarct scars increased intra- and postoperative risk and aneurysmectomy alone is considered insufficient for treatment of these disturbances. Further electrophysiologic investigations are needed and additional surgical measures may be necessary to improve the subset of patients with life-threatening arrhythmias.
尽管左心室动脉瘤切除术(LVA)是一种常见的外科手术,但其晚期功能和血液动力学结果尚未得到明确界定。本报告描述了1969年至1979年间接受LVA手术的135例患者的治疗结果。57例(42%)患者同时进行了相关手术,其中50例行冠状动脉搭桥术,5例行瓣膜置换术,2例行室间隔缺损修补术,3例为上述手术的联合应用。122例住院幸存者中的104例接受了2至107个月的随访(平均37个月)。住院死亡13例(9.6%),晚期死亡12例(9.8%),5年实际生存率为77%。术前心力衰竭的临床改善率为82%,心绞痛的改善率为70%。仅有33例患者(30%)恢复了正常工作。70例患者的自行车运动试验显示,41例(59%)的工作能力正常。49例患者再次进行心导管检查显示,左心室舒张末期压力或心脏指数无显著变化,总射血分数略有降低。术后通过长期心电图检测发现,70%的患者出现室性心律失常。术前有危及生命心律失常的患者中,50%的患者心律失常有所改善,但术后13例患者中只有2例无心律失常。本研究表明,与血液动力学和心电图改善相比,术后症状和功能改善更为常见。源自梗死灶后瘢痕的室性快速性心律失常增加了术中和术后风险,单纯动脉瘤切除术被认为不足以治疗这些紊乱。需要进一步的电生理检查,可能还需要采取额外的手术措施来改善有危及生命心律失常的患者亚组的情况。