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[干扰素及其在人和动物预防与治疗中的重要性]

[Interferons and their importance for prevention and therapy in man and animals].

作者信息

Selbitz H J, Scheel H, Voigt A, Schönherr W

出版信息

Z Gesamte Inn Med. 1980 Dec 1;35(23):837-41.

PMID:6162290
Abstract

In form of a survey of the actual international literature, taking into consideration own investigations, the present stage of knowledge concerning properties of interferones, inductors, course of synthesis and therapeutic mechanism is described. The effect of the interferones is in a manifold way connected with the effect of other factors of the infection defence, with complement, properdin, activity of phagocytosis and formation of antibodies. Though the application of interferone is still connected with great difficulties, encouraging results were yielded already in respiratory diseases and in tumour diseases, too. These results justify the performance of further experiments.

摘要

以对实际国际文献进行调查的形式,并考虑到自身的研究,描述了关于干扰素的特性、诱导剂、合成过程和治疗机制的当前知识阶段。干扰素的作用与感染防御的其他因素的作用以多种方式相关联,与补体、备解素、吞噬作用活性和抗体形成相关联。尽管干扰素的应用仍然面临很大困难,但在呼吸系统疾病和肿瘤疾病中也已经产生了令人鼓舞的结果。这些结果证明了进行进一步实验的合理性。

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