内侧杏仁核切开术和前海马切开术对癫痫患者行为和癫痫发作的影响。

The effect of medial amygdalotomy and anterior hippocampotomy on behavior and seizures in epileptic patients.

作者信息

Mempel E, Witkiewicz B, Stadnicki R, Luczywek E, Kuciński L, Pawłowski G, Nowak J

出版信息

Acta Neurochir Suppl (Wien). 1980;30:161-7. doi: 10.1007/978-3-7091-8592-6_20.

Abstract

In 70 patients with epilepsy and severe behavioural disturbances with EEG changes in the temporal regions, we performed EEG investigations of deep temporal structures, temporal cortex and scalp, using Talairach's stereotactic apparatus. Taking into account the recorded changes we performed 115 stereotactic lesions on the medial amygdala (both unilaterally and bilaterally) and on the anterior hippocampus (cornu Ammonis). The results in epileptic processes were: total recovery in 11.4%, evident clinical improvement in 74.3% and no improvement in 14.3%. Similar results were obtained in behavioural disturbances. Bilateral amygdalotomy and unilateral hippocampotomy in selected cases may produce recovery or amelioration and make possible return to normal social life for epileptic patients with severe behavioural changes.

摘要

在70例患有癫痫且伴有严重行为障碍以及颞区脑电图改变的患者中，我们使用Talairach立体定向装置对颞叶深部结构、颞叶皮质和头皮进行了脑电图检查。根据记录到的变化，我们在内侧杏仁核（单侧和双侧）以及前海马体（海马角）上进行了115次立体定向损伤。癫痫发作过程的结果为：11.4%完全恢复，74.3%有明显临床改善，14.3%无改善。行为障碍方面也得到了类似结果。在部分病例中，双侧杏仁核切开术和单侧海马切除术可能会带来恢复或改善，使伴有严重行为改变的癫痫患者有可能回归正常社会生活。