Hood T W, Siegfried J, Wieser H G
Appl Neurophysiol. 1983;46(1-4):19-25. doi: 10.1159/000101236.
The efficacy of bilateral stereotactic amygdalotomy for the treatment of aggressive behavioral disorders has been evaluated in a retrospective study of 67 cases. In addition 4 cases with complex partial seizures accompanied by aggressive outbursts revealing a unilateral epileptogenic focus in the amygdala or periamygdala region during preoperative stereoelectroencephalographic (SEEG) evaluation received a unilateral stereotactic amygdalotomy. Long-term follow-up of these 4 cases shows that 3 patients had considerable improvement in seizure frequency and severity as well as behavioral disturbances. The results in the remaining patients evaluated by surface EEG were inconclusive.
一项对67例患者的回顾性研究评估了双侧立体定向杏仁核切开术治疗攻击性行为障碍的疗效。另外，4例复杂部分性癫痫伴攻击性行为发作的患者，在术前立体脑电图（SEEG）评估中发现杏仁核或杏仁核周围区域存在单侧致痫灶，接受了单侧立体定向杏仁核切开术。对这4例患者的长期随访显示，3例患者的癫痫发作频率、严重程度及行为障碍均有显著改善。其余患者经头皮脑电图评估的结果尚无定论。
