Yamamoto S, Numata T, Yamura T
Ann Allergy. 1981 Feb;46(2):89-91.
Radioallergosorbent test (RAST) was performed on the sera obtained from chronic urticarial patients from whose leucocytes significant histamine release by mite antigen was observed. In 14 out of 19 cases investigated, no mite-antigen-specific IgE was detected in their sera by RAST, in spite of significant mite-antigen-induced histamine release from their leucocytes. The results suggest that type I reaction may be involved in chronic urticaria and the cell-bound, antigen-specific IgE may be important rather than the circulating antigen-specific IgE in this disease.
对从慢性荨麻疹患者身上获取的血清进行了放射变应原吸附试验（RAST），这些患者的白细胞经螨抗原刺激后可释放大量组胺。在19例受调查的病例中，有14例通过RAST在其血清中未检测到螨抗原特异性IgE，尽管其白细胞经螨抗原刺激后可释放大量组胺。结果表明，I型反应可能与慢性荨麻疹有关，在这种疾病中，细胞结合的抗原特异性IgE可能比循环中的抗原特异性IgE更重要。
